To BNP or not to BNP

To BNP or not to BNP.

Heart failure remains a major medical and social challenge despite the extraordinary progress in its diagnosis and treatment during the last 20 years. As a matter of fact, social factors such as the ageing of the population and the increase in longevity, both attributable to new treatments, will contribute to increase the burden of heart failure in future years. More than ever, we are in need o...

Neonatal calves affected by haemorrhages unrelated to BNP.

JUNE 2012 was the coolest June since 1998 and across southern and eastern Scotland it was the wettest June on record. Rainfall was 250 per cent to 300 per cent of normal in the Borders, Lothians and Fife, and the number of days with rain was among the highest in the past 50 years. In marked contrast, it was drier than average in Shetland and parts of the north-west and the Western Isles, with s...

Folic Acid Supplementation: to Advise or not to Advise?

Acute myocardial hypoxia increases BNP gene expression.

It is well established that cardiac failure increases cardiac B-type natriuretic peptide (BNP) expression due to myocardial stretching. However, patients with ischemic heart disease also display increased plasma BNP and proBNP concentrations despite preserved cardiac function. In this study, we examined whether acute myocardial hypoxia increases cardiac BNP expression. Surgical reduction of the...

Diastolic dysfunction and ANP/BNP levels.

[1] Brunotte F, Thompson CH, Adamopoulos S el al. Rat skeletal muscle metabolism in experimental heart failure: Effects of physical training. Acta Physiol Scand 1995; 154: 439-47. [2] Minotti JR, Johnson EC, Hudson TH et al. Skeletal muscle response to exercise training in congestive heart failure. J Clin Invest 1990; 86: 751-8. [3] Adamopoulos S, Coats AJ, Brunotte F el al. Physical training i...